| Product Name | XRCC6BP1 Antibody (FL-246) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-246 representing full length XRCC6BP1 of human origin |
| Modification Notes | XRCC6BP1, also known as mitochondrial inner membrane protease ATP23 homolog or KUB3, is a 246 amino acid protein. As a member of the peptidase M76 family, XRCC6BP1 interacts with XRCC6. The gene encoding XRCC6BP1 maps to human chromosome 12 and encodes Ku70 binding protein. Ku70 is a part of the DNA-dependent protein kinase complex and is involved in double-strand break repair. It is suggested that XRCC6BP1 gene amplification affects double-strand break repair in glioblastoma cell lines. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of XRCC6BP1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-246 representing full length XRCC6BP1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-246 representing full length XRCC6BP1 of human origin |
| Entrez Gene | 91419 |
|---|
| Application Notes | recommended for detection of XRCC6BP1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
