Application
Western blot analysis of MCAF2 expression in K-562 whole cell lysate.| Product Name | MCAF2 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminus of MCAF2 of human origin |
| Modification Notes | MCAF2 (MBD1-containing chromatin-associated factor 2), also known as ATF7IP2 (activating transcription factor 7-interacting protein 2), is a 682 amino acid nuclear protein that exists as two alternatively spliced isoforms. MCAF2 can act as either an activator or repressor, thereby modulating chromatin formation and/or transcription regulation by linking transcription factors to transcription apparatuses. A member of the MCAF family, MCAF2 contains one fibronectin type-III domain and is thought to form a complex with ESET and MBD1. The gene encoding MCAF2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MCAF2 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of MCAF2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of MCAF2 of human origin |
| Entrez Gene | 80063 |
|---|
Application
Western blot analysis of MCAF2 expression in K-562 whole cell lysate.| Application Notes | recommended for detection of MCAF2 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
