Application
Western blot analysis of DYNC2LI1 expression in non-transfected: (A) and mouse DYNC2LI1 transfected: (B) 293T whole cell lysates.| Product Name | DYNC2LI1 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminus of DYNC2LI1 of human origin |
| Modification Notes | Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic Dynein is an approximately twelve subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. Cytoplasmic Dynein performs functions necessary for cell survival such as organelle transport and centrosome assembly. DYNC2LI1 (dynein, cytoplasmic 2, light intermediate chain 1), also known as LIC3, D2LIC or CGI-60, is a 351 amino acid cytoplasmic protein belonging to the dynein light intermediate chain family. DYNC2LI1 may function as a motor for intraflagellar retrograde transport and in cilia biogenesis. The cytoplasmic dynein complex 2 may be composed of a DYNC2H1 homodimer and a number of DYNC2LI1 light intermediate chains. DYNC2LI1 exists as five alternatively spliced isoforms. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of DYNC2LI1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of DYNC2LI1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of DYNC2LI1 of human origin |
Application
Western blot analysis of DYNC2LI1 expression in non-transfected: (A) and mouse DYNC2LI1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of DYNC2LI1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
