Application
Western blot analysis of PIPK I expression in mouse brain (A) and rat testis (B) tissue extracts.| Product Name | PIPK I Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminus of PIPK I γ of human origin |
| Modification Notes | Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylin-ositol-4,5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking and cytoskeletal organization. The PIPK family is divided into type I, type II and type III. Each type of the PIPK family phosphorylates distinct substrates. They contain an activation loop, which determines their enzymatic specificity and subcellular targeting. The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I å, ∫ and ©, which are characterized by phosphorylating PI4P on the 5-hydroxyl. PIPK I å, designated PIPK I ∫ in mouse, is expressed in brain tissue. PIPK I ∫, designated PIPK I å in mouse, is also called STM7. PIPK I © has two variants produced by alternative splicing which are expressed in lung, brain and kidneys. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PIPK I α, β and γ of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of PIPK I &gamma of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of PIPK I γ of human origin |
| Entrez Gene | 23396 |
|---|
Application
Western blot analysis of PIPK I expression in mouse brain (A) and rat testis (B) tissue extracts.| Application Notes | recommended for detection of PIPK I α, β and γ of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
