Application
Western blot analysis of MAN2A1 expression in non-transfected: (A) and human MAN2A1 transfected: (B) 293T whole cell lysates.| Product Name | MAN2A1 Antibody (H-222) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 584-805 mapping within an internal region of MAN2A1 of human origin |
| Modification Notes | The alpha-mannosidases (designated MAN1A1, MAN1A2, MAN2A1 and MAN2A2) comprise a group of soluble proteins that localize to the endoplasmic reticulum, the golgi apparatus or the cytoplasm. Depending on their cellular location, these proteins are involved in either the processing or the degradation of newly synthesized N-glycans. MAN2A1 (mannosidase alpha class 2A member 1) is a single-pass type II membrane protein that localizes to the cisternae of the golgi and is involved in protein modification pathways. More specifically, MAN2A1 uses zinc as a cofactor to catalyze the first committed step in the formation of N-glycans, namely the hydrolysis of the terminal alpha-D-mannose residues in the oligosaccharide Man5(GlcNAc)3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MAN2A1 of human origin by WB, IP, IF and ELISA non cross-reactive with other MAN family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 584-805 mapping within an internal region of MAN2A1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 584-805 mapping within an internal region of MAN2A1 of human origin |
| Entrez Gene | 4124 |
|---|
Application
Western blot analysis of MAN2A1 expression in non-transfected: (A) and human MAN2A1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of MAN2A1 of human origin by WB, IP, IF and ELISA non cross-reactive with other MAN family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
