Application
Western blot analysis of MRGF expression in non-transfected: (A) and human MRGF transfected: (B) 293T whole cell lysates.| Product Name | MRGF Antibody (N-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an N-terminal extracellular domain of MRGF of human origin |
| Modification Notes | MRGF (MAS-related GPR, member F), also known as RTA, PSEC0142, GPR140 (G-protein coupled receptor 140) or GPR168 (G-protein coupled receptor 168), is a 343 amino acid multi-pass membrane protein that functions as an orphan receptor. MRGF belongs to the G-protein coupled receptor 1 family and Mas subfamily, and is thought to have a role in pain sensation and modulation by regulating nociceptor function. The gene encoding MRGF maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MRGF of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an N-terminal extracellular domain of MRGF of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an N-terminal extracellular domain of MRGF of human origin |
| Entrez Gene | 116535 |
|---|
Application
Western blot analysis of MRGF expression in non-transfected: (A) and human MRGF transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of MRGF of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
