| Product Name | TPTE Antibody (H-120) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 271-385 mapping within an internal region of TPTE of human origin |
| Modification Notes | TPTE (transmembrane phosphatase with tensin homology), also known as PTEN2 (phosphatase and tensin homolog 2) in mice or CT44 (cancer/testis antigen 44), is a 551 amino acid multi-pass membrane protein belonging to the PTEN-related family that is exclusively expressed in the testis and localizes to the plasma membrane in humans. The gene encoding TPTE is present in multiple copies in the human genome, some of which may be pseudogenes. TPTE contains one C2 tensin-type domain and one phosphatase tensin-type domain but, in humans, it does not exhibit phosphatase activity. However, the mouse ortholog (PTEN2) is a functional 3-phosphoinositide phosphatase that localizes to the Golgi apparatus and plays a possible role in signal transduction. In humans, four isoforms, namely TPTEå, TPTE∫, TPTE© and TPTE∂, are produced by alternative splicing of this gene. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TPTE of mouse, rat and human origin and TPTE2 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 271-385 mapping within an internal region of TPTE of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 271-385 mapping within an internal region of TPTE of human origin |
| Entrez Gene | 7179 |
|---|
| Application Notes | recommended for detection of TPTE of mouse, rat and human origin and TPTE2 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
