Application
Western blot analysis of C16orf62 expression in non-transfected 293T: (A), human C16orf62 transfected 293T: (B), MOLT-4 (C) and Raji (D) whole cell lysates.| Product Name | C16orf62 Antibody (T-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of C16orf62 of human origin |
| Modification Notes | C16orf62, also known as FLJ21040, MGC16824 or DKFZp313M0539, is a 963 amino acid membrane protein encoded by a gene mapping to human chromosome 16. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of C16orf62 isoforms 1 and 2 of human origin, 9030624J02Rik of mouse origin and the corresponding rat homolog by WB, IP, IF and ELISA non cross-reactive with other C16orf family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of C16orf62 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of C16orf62 of human origin |
| Entrez Gene | 57020 |
|---|
Application
Western blot analysis of C16orf62 expression in non-transfected 293T: (A), human C16orf62 transfected 293T: (B), MOLT-4 (C) and Raji (D) whole cell lysates.| Application Notes | recommended for detection of C16orf62 isoforms 1 and 2 of human origin, 9030624J02Rik of mouse origin and the corresponding rat homolog by WB, IP, IF and ELISA non cross-reactive with other C16orf family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
