| Product Name | FRAG1 Antibody (H-136) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 180-315 mapping at the C-terminus of FRAG1 of human origin |
| Modification Notes | The glycosylphosphatidylinositol (GPI)-anchored proteins are subjected to lipid remodeling during their biosynthesis. FRAG1 (FGF receptor-activating protein 1), also known as PGAP2 (post-GPI attachment to proteins 2) or CWH43-N (cell wall biogenesis 43 N-terminal homolog), is a 315 amino acid multi-pass membrane protein and a member of the PGAP2 family. Ubiquitously expressed, with highest levels in testis and pancreas, FRAG1 localizes to both the Endoplasmic reticulum and the Golgi apparatus. FRAG1 interacts with PGAP2IP and is involved in the lipid remodeling steps of GPI-anchor maturation. FRAG1 is required for stable expression of GPI-anchored proteins at the cell surface. Existing as three alternatively spliced isoforms, FRAG1 is conserved in chimpanzee, dog and Drosophila melanogaster, and encoded by a gene located on human chromosome 11p15.4. Chromosome 11 is comprised of 135 million base pairs encoding approximately 1,400 genes and makes up around 4% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of FRAG1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 180-315 mapping at the C-terminus of FRAG1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 180-315 mapping at the C-terminus of FRAG1 of human origin |
| Entrez Gene | 27315 |
|---|
| Application Notes | recommended for detection of FRAG1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
