| Product Name | PLC-XD2 Antibody (E-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of PLC-XD2 of human origin |
| Modification Notes | Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1,4,5-triphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. PLC isozymes are divided into subclasses based on structure and activation mechanisms. PLC-XD2 (PI-PLC X domain-containing protein 2) is a 305 amino acid protein that contains a domain that is present in many PLC isozymes, the PI-PLC X (X-box)domain. Both the X-box domain and the Y-box domain are important for catalytic activity in PLC proteins. X-box domains are conserved from prokaryotes to mammals. The gene encoding PLC-XD2 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. There are two isoforms of PLC-XD2 that are produced as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of PLC-XD2 of human origin by WB, IF and ELISA non cross-reactive with PLC-XD1 and 3 also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of PLC-XD2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of PLC-XD2 of human origin |
| Entrez Gene | 257068 |
|---|
| Application Notes | recommended for detection of PLC-XD2 of human origin by WB, IF and ELISA non cross-reactive with PLC-XD1 and 3 also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
