| Product Name | DPPX Antibody (H-77) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 668-744 mapping within an extracellular domain of DPPX of human origin |
| Modification Notes | Dipeptidyl peptidases (DPPs) mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1 (dipeptidyl-peptidase 8, DPP8, MSTP141), DPRP2 (dipeptidyl-peptidase 9, DPP9), DPP3 (DPPIII), DPRP3 (dipeptidyl-peptidase 10, DPP10, DPL2, DPPY, DPRP3), DPP6 (DPPX), DPP4 (adenosine deaminase complexing protein-2, T cell activation antigen CD26) and DPP7 (DPP2, QPP). DPPX, which can bind to the potassium channel KCND2, is a single-pass type II membrane protein. It is expressed mainly in brain tissues and may act as a modulator for cell surface expressed and activity of KCND2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of DPPX of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 668-744 mapping within an extracellular domain of DPPX of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 668-744 mapping within an extracellular domain of DPPX of human origin |
| Application Notes | recommended for detection of DPPX of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
