| Product Name | OBCAM Antibody (H-38) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 308-345 mapping at the C-terminus of OBCAM of human origin |
| Modification Notes | Opioid-binding cell adhesion molecule (OBCAM) is a glycosylphosphatidyl-inositol (GPI)-anchored neural cell adhesion molecule that binds opioids in the presence of acidic lipids. OBCAM consists of three immunoglobulin-like C2-type domains characteristic of members of the immunoglobulin superfamily and the IgLON subfamily, of which limbic system-associated membrane protein (LAMP) and neurotrimin (Ntm) are also members. Homophilic and heterophilic interactions between IgLON family members may play a role in the direction of neuronal projections by both promoting and inhibiting growth. During early rat brain development, OBCAM is highly expressed in post-mitotic neurons and in fiber tracts containing expanded axons. In adult rat brain, OBCAM is expressed primarily in the gray matter. OBCAM is also expressed in the hypothalamic magnocellular neurons, specifically in dendrites. OBCAM expression patterns suggest that it assists in axonal outgrowth processes and gives magnocellular neurons the ability to rearrange dendritic connectivity. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of OBCAM of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 308-345 mapping at the C-terminus of OBCAM of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 308-345 mapping at the C-terminus of OBCAM of human origin |
| Entrez Gene | 4978 |
|---|
| Application Notes | recommended for detection of OBCAM of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
