epitope mapping within an internal region of Aminopeptidase P3 of human origin
Modification Notes
Aminopeptidases comprise a family of enzymatic proteins that are widely distributed in both eukaryotes and prokaryotes and function to catalyze the removal of amino acids from the N-termini of proteins. Aminopeptidase P3, also known as APP3 or XPNPEP3, is a 507 amino acid protein that belongs to the aminopeptidase family. Expressed throughout the body, Aminopeptidase P3 uses manganese as a cofactor to catalyze the release of any proline-linked N-terminal amino acid, including those that exist in di- or tripeptides. Aminopeptidase P3 exists as three alternatively spliced isoforms which are encoded by a gene that maps to chromosome 22. Chromosome 22 houses over 500 genes, some of which are involved in Phelan-McDermid syndrome, schizophrenia and Neurofibromatosis type 2.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Aminopeptidase P3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of Aminopeptidase P3 of human origin
Tissue Specificity
epitope mapping within an internal region of Aminopeptidase P3 of human origin
Western blot analysis of Aminopeptidase P3 expression in mouse heart tissue extract.
Application Notes
recommended for detection of Aminopeptidase P3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.