| Product Name | ELOVL2 Antibody (H-57) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-57 mapping at the N-terminus of ELOVL2 of human origin |
| Modification Notes | Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as elongases and catalyze fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 2 (ELOVL2), also referred to as Ssc2 (sequence similarity to Cig30 2), is the human homolog of the yeast ELO2 protein. It is abundantly expressed in the testis, kidney and liver. ELOVL2 participates in the elongation of polyunsaturated fatty acids of 20 and 22 carbons thereby regulating the activity of PPARå. It has a narrow substrate preference which includes arachidonic acid and eicosapentaenoic acid. In addition, the overexpression of ELOVL2 enhances the synthesis of triacyglycerol (TAG). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ELOVL2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-57 mapping at the N-terminus of ELOVL2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-57 mapping at the N-terminus of ELOVL2 of human origin |
| Entrez Gene | 54898 |
|---|
| Application Notes | recommended for detection of ELOVL2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
