Application
Western blot analysis of ASXL1 expression in mouse testis (A) and mouse brain (B) tissue extracts.| Product Name | ASXL1 Antibody (N-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the N-terminus of ASXL1 of human origin |
| Modification Notes | ASXL1 (Additional sex combs-like protein 1) is a 1,541 amino acid protein encoded by the human gene ASXL1. ASXL1 belongs to the Asx family and contains one PHD-type zinc finger. It also contains one Leu-Xaa-Xaa-Leu-Leu (LXXLL) motif, which may be required for an association with nuclear receptors. ASXL1 is believed to be a Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. ASXL1 is a widely expressed nuclear protein with highest expression found in testis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ASXL1 of mouse and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of ASXL1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of ASXL1 of human origin |
| Entrez Gene | 171023 |
|---|
Application
Western blot analysis of ASXL1 expression in mouse testis (A) and mouse brain (B) tissue extracts.| Application Notes | recommended for detection of ASXL1 of mouse and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
