Application
Western blot analysis of TMCO3 expression in HeLa whole cell lysates.| Product Name | TMCO3 Antibody (D-19) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of TMCO3 of human origin |
| Modification Notes | TMCO3 (Transmembrane and coiled-coil domain-containing protein 3), also known as putative LAG1-interacting protein, is a 677 amino acid multi-pass membrane protein that probably functions as a Na+/H+ antiporter. TMCO3 belongs to the monovalent cation:protein antiporter 2 transporter family, a moderately large family of which members all share a very similar function under normal physiological conditions. The gene encoding TMCO3 maps to human chromosome 13, which comprises nearly 4% of human DNA and contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. There are three isoforms of TMCO3 that are produced as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TMCO3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of TMCO3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of TMCO3 of human origin |
| Entrez Gene | 55002 |
|---|
Application
Western blot analysis of TMCO3 expression in HeLa whole cell lysates.| Application Notes | recommended for detection of TMCO3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
