| Product Name | JHDM1D Antibody (S-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of JHDM1D of human origin |
| Modification Notes | JHDM1D (jumonji C domain containing histone demethylase 1 homolog D) is a 941 amino acid protein belonging to the JHDM1 histone demethylase family. Existing as two alternatively spliced isoforms, JHDM1D contains one JmjC domain and a PHD-type zinc finger. The gene encoding JHDM1D maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of JHDM1D isoforms 1 and 2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other JHDM1 family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of JHDM1D of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of JHDM1D of human origin |
| Entrez Gene | 80853 |
|---|
| Application Notes | recommended for detection of JHDM1D isoforms 1 and 2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other JHDM1 family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
