Application
Western blot analysis of CCDC4 expression in non-transfected: (A) and human CCDC4 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of CCDC4 expression in non-transfected: (A) and human CCDC4 transfected: (B) 293T whole cell lysates.| Product Name | BEND4 Antibody (T-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of BEND4 of human origin |
| Modification Notes | BEND4 (BEN domain-containing protein 4) is a 530 amino acid protein that contains a BEN domain. BEND4 exists as five alternatively spiced isoforms and is considered a complete proteome. BEN domain mediates protein–DNA and protein–protein interactions during chromatin organization and transcription. BEN domain may play a role in organization of viral DNA during replication or transcription. The BEND4 gene maps to human chromosome 4p13. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of BEND4 isoforms 1-3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other CCDC family members also reactive with additional species, including equine, canine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of BEND4 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of BEND4 of human origin |
| Entrez Gene | 389206 |
|---|
Application
Western blot analysis of CCDC4 expression in non-transfected: (A) and human CCDC4 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of CCDC4 expression in non-transfected: (A) and human CCDC4 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of BEND4 isoforms 1-3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other CCDC family members also reactive with additional species, including equine, canine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
