| Product Name | HYAL3 Antibody (H-82) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 37-118 mapping near the N-terminus of HYAL3 of human origin |
| Modification Notes | Hyaluronidases (HAases or HYALs) are a family of lysosomal enzymes that are crucial for the spread of bacterial infections and of toxins present in a variety of venoms. HYALs may also be involved in the progression of cancer. In humans, six HYAL proteins have been identified. HYAL proteins use hydrolysis to degrade hyaluronic acid (HA), which is present in body fluids, tissues, and the extracellular matrix of vertebrate tissues. HA keeps tissues hydrated, maintains osmotic balance, and promotes cell proliferation, differentiation, and metastasis. HA is also an important structural component of cartilage and acts as a lubricant in joints. HYAL3 is a 417-amino acid protein that is highly expressed in testis and bone marrow, but has relatively low expression in all other tissues. Unlike HYAL 1 and HYAL2, HYAL3 is an unlikely tumor supressor candidate, given the lack of detected mutations in its gene. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of HYAL3 of human, and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 37-118 mapping near the N-terminus of HYAL3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 37-118 mapping near the N-terminus of HYAL3 of human origin |
| Application Notes | recommended for detection of HYAL3 of human, and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
