| Product Name | ZNRD1 Antibody (H-56) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 71-126 mapping at the C-terminus of ZNRD1 of human origin |
| Modification Notes | ZNRD1 (zinc ribbon domain containing 1), also known as TEX6, Rpa12 or hZR14, is a 126 amino acid protein that localizes to the nucleolus and contains one TFIIS-type zinc finger. Existing as a component of the multi-protein Pol I (RNA polymerase I) complex, ZNRD1 functions as a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA and plays a role in the synthesis of ribosomal RNA (rRNA) precursors. The gene encoding ZNRD1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ZNRD1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 71-126 mapping at the C-terminus of ZNRD1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 71-126 mapping at the C-terminus of ZNRD1 of human origin |
| Entrez Gene | 30834 |
|---|
| Application Notes | recommended for detection of ZNRD1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
