Application
Western blot analysis of Bestrophin-2 expression in non-transfected: (A) and mouse Bestrophin-2 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of Bestrophin-2 expression in non-transfected: (A) and mouse Bestrophin-2 transfected: (B) 293T whole cell lysates.| Product Name | Bestrophin-2 Antibody (H-188) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 322-509 mapping at the C-terminus of Bestrophin-2 of human origin |
| Modification Notes | Bestrophin-2, also known as BEST2 or VMD2L1 (Vitelliform macular dystrophy 2-like protein 1), is a 509 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-2 forms a calcium-sensitive chloride channel located within the cell membrane. It is also believed that Bestrophin-2 channels may also conduct other physiological anions such as bicarbonate. Bestrophin-2 is mainly expressed in retinal pigment epithelium and colon. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Bestrophin-2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 322-509 mapping at the C-terminus of Bestrophin-2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 322-509 mapping at the C-terminus of Bestrophin-2 of human origin |
| Entrez Gene | 54831 |
|---|
Application
Western blot analysis of Bestrophin-2 expression in non-transfected: (A) and mouse Bestrophin-2 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of Bestrophin-2 expression in non-transfected: (A) and mouse Bestrophin-2 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of Bestrophin-2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
