Application
Western blot analysis of PNO1 expression in non-transfected 293T: (A), mouse PNO1 transfected 293T: (B) and K-562 (C) whole cell lysates.| Product Name | PNO1 Antibody (D-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of PNO1 of human origin |
| Modification Notes | PNO1 (partner of NOB1), also known as KHRBP1, is a 252 amino acid protein that localizes to the nucleolus and contains one KH domain. Expressed in a variety of tissues, including kidney, lung, liver and spleen, with lower levels present in brain, heart, colon and skeletal muscle, PNO1 may play a role in RNA binding events during transcription or translation. The gene encoding PNO1 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alström syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PNO1 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of PNO1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of PNO1 of human origin |
| Entrez Gene | 56902 |
|---|
Application
Western blot analysis of PNO1 expression in non-transfected 293T: (A), mouse PNO1 transfected 293T: (B) and K-562 (C) whole cell lysates.| Application Notes | recommended for detection of PNO1 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
