epitope corresponding to amino acids 31-100 mapping near the N-terminus of CHSY2 of human origin
Modification Notes
Chondroitin sulfate synthases (CHSYs) synthesize chondroitin sulfate, a glycosaminoglycan expressed on the surface of most cells and in extracellular matrices. Glycosaminoglycan chains are covalently linked to various of core protein families and regulate many biologic processes, including extracellular matrix deposition, cell proliferation and recognition, and morphogenesis. The CHSY family includes CHSY1, CHSY2 and CHSY3. CHSY1 and CHSY3 display both glucuronyltransferase and N-acetylgalactosaminyltransferase activities, while CHSY2 is required for chondroitin polymerizing activity. CHSY2 localizes to the Golgi apparatus and is expressed ubiquitously, with highest expression observed in the pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of CHSY2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 31-100 mapping near the N-terminus of CHSY2 of human origin
Tissue Specificity
epitope corresponding to amino acids 31-100 mapping near the N-terminus of CHSY2 of human origin
Western blot analysis of CHSY2 expression in non-transfected: (A) and mouse CHSY2 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of CHSY2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.