| Product Name | Paraxis Antibody (H-55) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 4-42 mapping at the N-terminus of Paraxis of human origin |
| Modification Notes | The novel basic helix-loop-helix (bHLH) transcription factor, twist, is a putative regulator of mesodermal differentiation and myogenesis. Twist is expressed throughout the epithelial somite but not in the myotome. Twist requires dimerization with E proteins, such as Paraxis, and inhibits myogenic regulatory factors. As an early transcriptional regulator, Paraxis determines the mesoderm pattern and governs the type of mesoderm-derived cells. Paraxis is also involved in the regulaton of morphogenetic activites during somitogenesis. Paraxis, a nuclear protein containing one bHLH domain, requires dimerization with another protein in order to bind DNA efficiently. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Paraxis of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 4-42 mapping at the N-terminus of Paraxis of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 4-42 mapping at the N-terminus of Paraxis of human origin |
| Entrez Gene | 6939 |
|---|
| Application Notes | recommended for detection of Paraxis of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
