Application
Western blot analysis of Wnt-2b expression in mouse brain tissue extract.| Product Name | Wnt-2b Antibody (H-39) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 263-301 mapping within an internal region of Wnt-2b of human origin |
| Modification Notes | The Wnt family of protooncogenes consists of at least 13 known members which encode secreted signaling proteins that are involved in oncogenesis and several other developmental processes, such as regulation of cell fate and embryogenesis. Wnt-2b (wingless-type MMTV integration site family, member 2B), also known as WNT13 or XWNT2, is a 391 amino acid protein that is secreted into the extracellular matrix and belongs to the Wnt family. Expressed as two isoforms, the first of which is present primarily in adult tissues and the second of which is present primarily in fetal tissues, Wnt-2b functions as a ligand for transmembrane receptor proteins and is thought to play a role in tissue differentiation and development. Wnt-2b is expressed in a variety of cancer cell lines, suggesting a role in tumorigenesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Wnt-2b of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 263-301 mapping within an internal region of Wnt-2b of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 263-301 mapping within an internal region of Wnt-2b of human origin |
| Entrez Gene | 7482 |
|---|
Application
Western blot analysis of Wnt-2b expression in mouse brain tissue extract.| Application Notes | recommended for detection of Wnt-2b of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
