Application
Western blot analysis of PDSS1 expression in Hep G2 whole cell lysate.| Product Name | PDSS1 Antibody (F-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of PDSS1 of mouse and human origin by WB, IP and ELISA |
| Modification Notes | PDSS1, Decaprenyl-diphosphate synthase subunit 1, is a magnesium binding peptide that belongs to the FPP/GGPP synthetase family. Forming a heterotetramer that consists of 2 DPS1/TPRT and 2 DLP1 subunits, Decaprenyl-diphosphate synthase functions to supply decaprenyl diphosphate, which is the precursor for the side chains of the isoprenoid quinones ubiquinone-10. Limited expression or defects of PDSS1 can lead to a coenzyme Q10 deficiency which can be manifested by several phenotypes. Coenzyme Q10 (CoQ10) deficiencies can lead to reduced ATP synthesis and result in marked cerebellar atrophy and pure myopathy. CoQ10 deficiencies has also been associated with reversible renal diseases and infantile multisystemic and cerebellar ataxia. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of PDSS1 of mouse and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of PDSS1 of mouse and human origin by WB, IP and ELISA |
| Entrez Gene | 23590 |
|---|
Application
Western blot analysis of PDSS1 expression in Hep G2 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
