epitope corresponding to amino acids 126-220 mapping within an internal region of PHF13 of human origin
Modification Notes
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF13 (PHD finger protein 13), also known as PHF5 or SPOC1, is a 300 amino acid protein that contains one PHD-type zinc finger, suggesting involvement in transcriptional regulation events. The gene encoding PHF13 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of PHF13 of mouse, rat and human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 126-220 mapping within an internal region of PHF13 of human origin
Tissue Specificity
epitope corresponding to amino acids 126-220 mapping within an internal region of PHF13 of human origin