| Product Name | GCM1 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 137-436 mapping at the C-terminus of GCM1 of human origin |
| Modification Notes | GCM1 (glial cells missing homolog 1), also known as GCMA or hGCMa, is a 436 amino acid human homolog of the Drosophila glial cells missing protein (gcm). Localized to the nucleus and expressed specifically in placenta, GCM1 functions as a transcription factor that binds the novel sequence (A/G)CCCGCAT and, through this binding, regulates placental development. Additionally, GCM1 is thought to regulate syncytin SU-mediated trophoblastic fusion, an event that produces syncytiotrophoblast structures which, in turn, function as the outermost covering of the placental villi. GCM1 contains one N-terminal GCM (glial cell missing) DNA-binding domain, a conserved 150 amino acid residue that conveys DNA-binding activity for a variety of transcription factors involved in developmental processes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of GCM1 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 137-436 mapping at the C-terminus of GCM1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 137-436 mapping at the C-terminus of GCM1 of human origin |
| Entrez Gene | 8521 |
|---|
| Application Notes | recommended for detection of GCM1 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
