Application
Western blot analysis of LSM6 expression in non-transfected: (A) and human LSM6 transfected: (B) 293 whole cell lysates.| Product Name | LSm6 Antibody (H-40) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-40 mapping at the N-terminus of LSm6 of human origin |
| Modification Notes | Sm and Sm-like (LSm) proteins form donut-shaped, ubiquitously expressed heptameric complexes that are involved in various steps of RNA metabolism, including RNA-protein interactions and structural changes that are required during ribosomal subunit assembly. LSm6 is an 80 amino acid protein that localizes to both the nucleus and the cytoplasm and belongs to the LSm subfamily of snRNP Sm proteins. Functioning as a component of the heptameric LSm1-LSm7 complex, LSm6 is involved in mRNA degradation, specifically by activating the decapping step in the 5'-to-3' mRNA decay pathway. Additionally, LSm6 plays a role in facilitating the association of RNA processing factors with their substrates and may also be involved in the processing of tRNAs. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LSm6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-40 mapping at the N-terminus of LSm6 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-40 mapping at the N-terminus of LSm6 of human origin |
| Entrez Gene | 11157 |
|---|
Application
Western blot analysis of LSM6 expression in non-transfected: (A) and human LSM6 transfected: (B) 293 whole cell lysates.| Application Notes | recommended for detection of LSm6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
