| Product Name | GS2 Antibody (H-115) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 46-160 mapping within an internal region of GS2 of human origin |
| Modification Notes | The Adiponutrin family consists of Adiponutrin (ADPN), adipocyte triglyceride lipase (ATGL, also designated Desnutrin), GS1, GS2, GS2-like and PNPLA1. ADPN, ATGL and GS2 display lipase activity, which is dependent upon the presence of an activated serine residue. GS2, also designated DXS1283E or patatin-like phospholipase domain containing 4 (PNPLA4), is expressed in all tissues that have been examined, including brain, heart, lung, muscle, placenta, liver, spleen, pancreas, and kidney. It is also expressed highly in adipose tissue and may contribute to lipolysis in human adipose tissue. GS2-like, also designated patatin-like phospholipase domain containing 5 (PNPLA5), is expressed and regulated similarly to ADPN, although the levels of GS2-like mRNA are lower than ADPN. Overexpression of GS2, GS2-like, and ATGL lowers intracellular triglyceride levels. GS2-like and ADPN are strongly induced in the liver of ob/ob mice. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of GS2 of human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 46-160 mapping within an internal region of GS2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 46-160 mapping within an internal region of GS2 of human origin |
| Entrez Gene | 8228 |
|---|
| Application Notes | recommended for detection of GS2 of human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
