| Product Name | REPS2 Antibody (H-145) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 141-285 mapping within an internal region of REPS2 of human origin |
| Modification Notes | REPS2, a cytoplasmic protein, is primarily expressed in cerebellum, lung, testis, cerebrum, and kidney. REPS2 forms as complex with DDEF1 and then binds to paxillin. It can also form a complex with activated RAL, which interacts with the Rho subfamily member Cdc42, and with RAL BP-1, which is involved in growth factor signaling via its influence on the RAL signaling pathway. The NF-˚B subunit p65 interacts with the EH domain of REPS2, and an upregulation of NF-˚B activity correlates with a downregulation of REPS2 activity. Decreased expression of REPS2 during progression cancer cells may lead to loss of control of growth factor signalling and, thus, loss of control of cell proliferation. REPS2 may also be an important factor in cancer cell resistance to apoptosis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of REPS2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 141-285 mapping within an internal region of REPS2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 141-285 mapping within an internal region of REPS2 of human origin |
| Entrez Gene | 9185 |
|---|
| Application Notes | recommended for detection of REPS2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
