Application
Western blot analysis of DAPK2 expression in mouse lung tissue extract.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human skeletal muscle tissue showing cytoplasmic localization.| Product Name | DAPK2 Antibody (P-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of DAPK2 of mouse and human origin by WB, IP, IF, IHC(P) and ELISA |
| Modification Notes | Death-associated protein kinase 2 (DAPK2), also designated death-associated protein kinase-related protein-1 (DRP-1), is a calcium/calmodulin-regulated serine/threonine kinase that binds to calmodulin, undergoes autophosphorylation in response to an increase in cellular calcium concentration, and phosphorylated myosin light chain (MLC) as an exogenous substrate. DAPK2 is expressed in heart, lung, and skeletal muscle and is localized to the cytoplasm. DAPK2 displays significant homology to DAP-kinase, which mediates interferon (IFN)-g-induced apoptosis in HeLa. Subsequently, DAPK2 is thought to function as a possible tumor suppressor gene. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of DAPK2 of mouse and human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of DAPK2 of mouse and human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 23604 |
|---|
Application
Western blot analysis of DAPK2 expression in mouse lung tissue extract.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human skeletal muscle tissue showing cytoplasmic localization.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
