| Product Name | SRp55 Antibody (H-180) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-180 mapping at the N-terminus of SRp55 of human origin |
| Modification Notes | Pre-mRNA splicing is a critical step in the post-transcriptional regulation of gene expression. Several protein complexes are involved in proper mRNA splicing and transport. Serine/arginine-rich (SR) proteins SRp55, SRp30c, and htra2beta1 regulate exon 2 and 10 splicing. The first two inhibit both exons and SRp55 also plays a role in exon inclusion after the removal of intronic splicing silencer sequences. SRp55 plays a major role in maintaining normal FGFR1 alpha-exon inclusion. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SRp55 and, to a lesser extent, SRp75, SRp40 and other family members of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-180 mapping at the N-terminus of SRp55 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-180 mapping at the N-terminus of SRp55 of human origin |
| Entrez Gene | 6431 |
|---|
| Application Notes | recommended for detection of SRp55 and, to a lesser extent, SRp75, SRp40 and other family members of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
