| Product Name | ATP11B Antibody (P-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within a cytoplasmic domain of ATP11B of human origin |
| Modification Notes | ATP11B (ATPase, class VI, type 11B), also known as ATPIR or ATPIF, is a 1,177 amino acid multi-pass membrane protein that belongs to the cation transport family of P-type ATPases. Like most P-type ATPases, ATP11B is phosphorylated in its intermediate state and it uses ATP to drive the active transport of ions across cellular membranes. ATP11B, which contains 10 transmembrane domains, is expressed at high levels in ovary, kidney, testis and corpus callosum and is encoded by a gene that maps to human chromosome 3. Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ATP11B of human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within a cytoplasmic domain of ATP11B of human origin |
|---|---|
| Tissue Specificity | epitope mapping within a cytoplasmic domain of ATP11B of human origin |
| Entrez Gene | 23200 |
|---|
| Application Notes | recommended for detection of ATP11B of human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
