| Product Name | BTR1 Antibody (M-270) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 51-320 mapping near the N-terminus of BTR1 of mouse origin |
| Modification Notes | BTR1 (Bicarbonate transporter-related protein 1), also known as sodium bicarbonate transporter-like protein 11, sodium-coupled borate cotransporter 1 (NaBC1) or solute carrier family 4 member 11 (SLC4A11), belongs to the anion exchanger family of proteins. BTR1 is ubiquitously expressed, localizes to the plasma membrane and exists as a multi-pass membrane protein. It functions as an electrogenic Na+-dependent borate transporter and is essential for cell growth, proliferation and borate homeostasis. In the absence of borate, BTR1 functions as a conductive transporter, permeable to Na+ and H+. Several different mutations in BTR1 result in recessive congenital hereditary endothelial dystrophy (CHED2), a rare eye disorder characterized by corneal opacification and involuntary eye movement (nystagmus). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of BTR1 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 51-320 mapping near the N-terminus of BTR1 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 51-320 mapping near the N-terminus of BTR1 of mouse origin |
| Entrez Gene | 83959 |
|---|
| Application Notes | recommended for detection of BTR1 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
