Application
Western blot analysis of Angptl4 expression in non-transfected: (A) and mouse Angptl4 transfected: (B) 293T whole cell lysates.| Product Name | Angptl4 Antibody (M-200) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 56-255 mapping near the N-terminus of Angptl4 of mouse origin |
| Modification Notes | Angiopoietin-like 4 (Angptl4), also designated hepatic fibrinogen/angiopoietin-related protein (HFARP), is a secreted protein which, through an endocrine action, exerts a protective function over endothelial cells. The Angptl4 gene has hypoxia-induced expression in endothelial cells. Angptl4 has a highly hydrophobic region at the N-terminus that is typical of a secretory signal sequence and one consensus glycosylation site. Angptl4 is considered a marker of renal cell carcinoma (other renal tumor cells do not produce Angptl4 mRNA). Evidence suggests that Angptl4 is a blood-borne hormone directly involved in regulating glucose homeostasis, lipid metabolism and insulin sensitivity. Angptl4 exerts distinct effects on glucose and lipid metabolism, and may be useful for the treatment of diabetes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Angptl4 of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 56-255 mapping near the N-terminus of Angptl4 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 56-255 mapping near the N-terminus of Angptl4 of mouse origin |
| Entrez Gene | 57875 |
|---|
Application
Western blot analysis of Angptl4 expression in non-transfected: (A) and mouse Angptl4 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of Angptl4 of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
