epitope mapping near the C-terminus of TRIM65 of human origin
Modification Notes
The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B box-type zinc finger, one RING finger and three zinc-binding domains. TRIM proteins are involved in a wide variety of cellular processes such as cell development, proliferation, differentiation, oncogenesis and apoptosis. Many TRIM proteins are induced by type I and type II interferons, making them crucial for development of pathogen-resistance. TRIM65 (tripartite motif containing 65), is a 517 amino acid protein that belongs to the TRIM/RBCC family. Containing a B box-type zinc finger, a B30.2/SPRY domain and a RING-type zinc finger, TRIM65 is encoded by a gene located on human chromosome 17q25.1. Chromosome 17 makes up over 2.5% of the human genome, with about 81 million bases encoding over 1,200 genes.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TRIM65 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TRIM family members also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the C-terminus of TRIM65 of human origin
Tissue Specificity
epitope mapping near the C-terminus of TRIM65 of human origin
Western blot analysis of TRIM65 expression in non-transfected: (A) and human TRIM65 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of TRIM65 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TRIM family members also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.