Application
Western blot analysis of RBM45 expression in Jurkat (A), MCF7 (B) and U-87 MG (C) whole cell lysates and mouse testis tissue extract (D).Application
Western blot analysis of RBM45 expression in Hep G2 whole cell lysate.| Product Name | RBM45 Antibody (I-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against RBM45 of human origin |
| Modification Notes | The RBM (RNA-binding motif) gene family encodes proteins with an RNA binding motif. RBM45, also known as developmentally-regulated RNA-binding protein 1 (DRB1), is a 476 amino acid protein that may play an important role in neural development. Structurally, RBM45 has four RNA recognition motifs (RRMs), however, due to a sequence divergence, it has been suggested that only three of the RRMs functionally bind RNA. These structural motifs are similar to those found in other neural RNA-binding proteins, such as Msi1, Hel-N1 and HuC, but RBM45 differs from these functionally similar proteins because it has a poly(C) RNA-binding preference. RBM45 is predominantly localized to the cytoplasm, but has also been shown to shuttle to the nucleus. Supporting its suggested role in neuronal development, RBM45 expression is highest in neuronal pregenitor cells, but is reduced in differentiated neural cells. There are three isoforms of RBM45 as a result of alternative splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of RBM45 of mouse, rat, human and canine origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against RBM45 of human origin |
|---|---|
| Tissue Specificity | raised against RBM45 of human origin |
| Entrez Gene | 129831 |
|---|
Application
Western blot analysis of RBM45 expression in Jurkat (A), MCF7 (B) and U-87 MG (C) whole cell lysates and mouse testis tissue extract (D).
Application
Western blot analysis of RBM45 expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of RBM45 of mouse, rat, human and canine origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
