epitope corresponding to amino acids 1-245 representing full length NESP55 of human origin
Modification Notes
NESP55 (neuroendocrine secretory protein 55), also known as AHO, GSA, GSP, POH, GPSA, NESP, GNAS1, PHP1A or PHP1B, is a 245 amino acid precursor protein that is proteolytically processed to yield a number of active peptides that localize to neuroendocrine secretory granules and have diverse roles throughout the body. Defects or genetic variations in the NESP55 gene are associated with the pathogenesis of a variety of disorders, including ACTH-independent macronodular adrenal hyperplasia (AIMAH), Albright hereditary osteodystrophy, polyostotic fibrous dysplasia of bone, McCune-Albright syndrome, pseudohypoparathyroidis, pseudopseudohypoparathyroidism, progressive osseus heteroplasia and pituitary tumors.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of NESP55 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-245 representing full length NESP55 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-245 representing full length NESP55 of human origin
Western blot analysis of NESP55 expression in Ramos whole cell lysate.
Application Notes
recommended for detection of NESP55 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.