Application
Western blot analysis of NSBP1 expression in Hep G2 whole cell lysate.| Product Name | NSBP1 Antibody (M-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against NSBP1 of human origin |
| Modification Notes | The high-mobility group (HMG) proteins 14 and 17 are abundant chromosomal proteins that bind to nucleosomes and enhance transcription. HMG-14 and HMG-17 also function as architectural elements, which alter the structure of the chromatin fiber and enhance transcription from chromatin templates. HMG-14/17 proteins modify the nucleosomal organization of the 30 nm chromatin fiber and mediate the unfolding of the higher order chromatin structure thereby facilitating access to the underlying DNA sequence. The nucleosomal binding protein 1 (NSBP1) is highly homologous to the HMG-14 and HMG-17 proteins and plays a pivotal role in chromatin remodeling. The human NSBP1 gene produces three mRNA transcripts with alternate polyadenylated sites, which are thought to mediate the stability of the mRNA. In androgen-independent prostate cancer cells, NSBP1 promotes cell growth and viability, which subsequently, makes NSBP1 a potential target for therapeutic purposes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of NSBP1 of human origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against NSBP1 of human origin |
|---|---|
| Tissue Specificity | raised against NSBP1 of human origin |
| Entrez Gene | 79366 |
|---|
Application
Western blot analysis of NSBP1 expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of NSBP1 of human origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
