| Product Name | HSP 90 Antibody (at-115) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 585-699 mapping at the C-terminus of HSP 90 of Arabidopsis thaliana origin |
| Modification Notes | The heat shock response was first described for Drosophila salivary gland cells and morphologically consists of a change in their polytene chromosome puffing patterns that involves de novo synthesis of a few proteins. Similar heat shock proteins were later discovered in bacterial chicken and mammalian cells, and have been subsequently studied in other organisms. A series of proteins, including HSP 90, HSP 70, HSP 20-30 and ubiquitin, are induced by insults such as temperature shock, chemicals and other environmental stress. A major function of HSP 90 and other HSPs is to act as molecular chaperones. HSP 90 forms a complex with glucocorticoid receptor (GR), rendering the non ligand-bound receptor transcriptionally inactive. HSP 90 binds the GR as a heterocomplex composed of either HSP 56 or Cyclophilin D, forming an aporeceptor complex. HSP 90 also exists as a dimer with other proteins such as p60/STI1 and p23, forming an thumper complex with estrogen and androgen receptors. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of HSP 90 of Arabidopsis thaliana, Nicotiana tabacum, Lycopersicon esculentum and Zea mays origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 585-699 mapping at the C-terminus of HSP 90 of Arabidopsis thaliana origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 585-699 mapping at the C-terminus of HSP 90 of Arabidopsis thaliana origin |
| Application Notes | recommended for detection of HSP 90 of Arabidopsis thaliana, Nicotiana tabacum, Lycopersicon esculentum and Zea mays origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
