Application
Western blot analysis of PGF2αR expression in HeLa (A), HT-1080 (B) and PC-3 (C) whole cell lysates.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human pre-menopausal uterus tissue showing cytoplasmic staining of glandular cells and cells in endometrial stroma| Product Name | PGF2αR Antibody (H-55) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 56-110 mapping near the N-terminus of PGF2αR of human origin |
| Conjugation | Agarose |
| Modification | Acetylated |
| Modification Notes | Prostaglandin receptors are integral membrane proteins that bind prostaglandins with high affinity. This triggers changes in the cell which influence cell behaviour. Prostaglandin receptor subtypes are named according to their relative affinities for the endogenous prostaglandins. These include prostaglandin D2 (DP receptors), prostaglandin E2 (EP1, EP2, and EP3 receptors), prostaglandin F2-alpha (FP receptors), and prostacyclin (IP receptors). Prostaglandin F2-alpha receptor (PGF2åR), also designated prostanoid FP receptor is an integral membrane protein. It acts as a receptor for prostaglandin F2-alpha. The activity of PGF2åR is mediated by G proteins that activate phosphatidylinositol-calcium second messenger system. In the corpus luteum, PGF2åR is involved in luteolysis initiation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIPWB |
| WB:1:100~1:500 IP:1:20~1:100 IF:1:20~1:100 |
|
| Species Reactivity | HumanMouseRat |
| Predicted Reactivity | equine, canine, porcine, avian and feline |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 56-110 mapping near the N-terminus of PGF2αR of human origin |
|---|---|
| Molecular Weight(MW) | 40 kDa |
| Tissue Specificity | epitope corresponding to amino acids 56-110 mapping near the N-terminus of PGF2αR of human origin |
Application
Western blot analysis of PGF2αR expression in HeLa (A), HT-1080 (B) and PC-3 (C) whole cell lysates.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human pre-menopausal uterus tissue showing cytoplasmic staining of glandular cells and cells in endometrial stroma| Application Notes | WB:1:100~1:500 IP:1:20~1:100 IF:1:20~1:100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
