epitope mapping within an internal region of TBC1D19 of human origin
Modification Notes
TBC1D19 (TBC1 domain family member 19) is a 526 amino acid protein that contains one Rab-GAP TBC domain and may act as a GTPase-activating protein for Rab family proteins. The gene that encodes TBC1D19 contains 178,915 bases and maps to human chromosome 4p15.2. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded by a gene located on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TBC1D19 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TBC1D family members also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of TBC1D19 of human origin
Tissue Specificity
epitope mapping within an internal region of TBC1D19 of human origin
Western blot analysis of TBC1D19 expression in non-transfected: (A) and human TBC1D19 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of TBC1D19 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TBC1D family members also reactive with additional species, including equine, canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.