| Product Name | SAS10 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 180-479 mapping at the C-terminus of SAS10 of human origin |
| Modification Notes | SAS10 (something about silencing protein 10), also known as UTP3 or CRLZ1 (charged amino acid-rich leucine zipper 1), is a small subunit (SSU) processome component. The SSU processome is a complex involved in ribosome biogenesis and is required for pre-18S rRNA maturation. SAS10 localizes to the nucleus and also plays a role in forming the structure of silenced chromatin. SAS10 is the human homolog of the S. cerevisiae Sas10 protein. In S. cerevisiae, the overexpression of Sas10 disrupts gene silencing. This suggests another role of SAS10 in gene silencing. In addition, SAS10 is believed to be involved in the development of the brain. Upon DNA damage, SAS10 is phosphorylated by ATM or ATR. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SAS10 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 180-479 mapping at the C-terminus of SAS10 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 180-479 mapping at the C-terminus of SAS10 of human origin |
| Entrez Gene | 57050 |
|---|
| Application Notes | recommended for detection of SAS10 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
