Application
Western blot analysis of PRR18 expression in non-transfected: (A) and human PRR18 transfected: (B) 293T whole cell lysates.| Product Name | PRR18 Antibody (S-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of PRR18 of human origin |
| Modification Notes | Proline-rich proteins are often involved in protein-protein interactions and typically act as ligands for SH3, WW and EVH1 domains. PRR18 (proline rich 18) is a 295 amino acid protein that is encoded by a gene that maps to human chromosome 6q27 and mouse chromosome 17 A1. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PRR18 of human origin by WB, IP, IF and ELISA non cross-reactive with other PRR family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of PRR18 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of PRR18 of human origin |
| Entrez Gene | 285800 |
|---|
Application
Western blot analysis of PRR18 expression in non-transfected: (A) and human PRR18 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of PRR18 of human origin by WB, IP, IF and ELISA non cross-reactive with other PRR family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
