| Product Name | TMEM18 Antibody (S-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an N-terminal extracellular domain of TMEM18 of human origin |
| Modification Notes | TMEM18 (Transmembrane protein 18) is a 140 amino acid multi-pass membrane protein that localizes to the nuclear membrane and is expressed in the brain. TMEM18 functions as a cell migration modulator which enhances the glioma-specific migration ability of neural precursor and neural stem cells.Overexpression of TMEM18 increases migration of human and murine neural stem cells, whereas knockdown of TMEM18 mRNA reduces cellular migration. Two specific single nucleotide polymorphisms (SNPs) within the TMEM18 gene locus known as rs6548238 and rs756131 have been linked to obesity susceptibility. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of TMEM18 isoform 1 of human origin by WB, IF and ELISA non cross-reactive with isoforms TMEM18-2 non cross-reactive with other TMEM family members also reactive with additional species, including bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an N-terminal extracellular domain of TMEM18 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an N-terminal extracellular domain of TMEM18 of human origin |
| Entrez Gene | 129787 |
|---|
| Application Notes | recommended for detection of TMEM18 isoform 1 of human origin by WB, IF and ELISA non cross-reactive with isoforms TMEM18-2 non cross-reactive with other TMEM family members also reactive with additional species, including bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
