Application
Western blot analysis of CYP2J2 expression in Hep G2 whole cell lysate.Application
Western blot analysis of CYP2J2 expression in mouse heart tissue extract.| Product Name | CYP2J6 Antibody (M-60) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-60 mapping at the N-terminus of CYP2J6 of mouse origin |
| Modification Notes | Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). Murine CYP2J6 (cytochrome P450, family 2, subfamily j, polypeptide 6), also known as CYPIIJ6 or arachidonic acid epoxygenase, is a 501 amino acid peripheral membrane protein of the endoplasmic reticulum and microsome that belongs to the cytochrome P450 family. Highly expressed in small intestine, CYP2J6 assists in the metabolism of benzphetamine, but not arachidonic acid, and is encoded by a gene located on murine chromosome 4 C5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CYP2J6 of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-60 mapping at the N-terminus of CYP2J6 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-60 mapping at the N-terminus of CYP2J6 of mouse origin |
| Entrez Gene | 13110 |
|---|
Application
Western blot analysis of CYP2J2 expression in Hep G2 whole cell lysate.
Application
Western blot analysis of CYP2J2 expression in mouse heart tissue extract.| Application Notes | recommended for detection of CYP2J6 of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
