| Product Name | robo4 Antibody (H-230) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 546-775 mapping within an internal region of robo4 of human origin |
| Modification Notes | Secreted leucine-rich repeat-containing proteins 1 through 3 (Slit1-3) are secreted glycoproteins that influence axonal guidance and mediate normal neural progression by acting as high-affinity signaling ligands for the repulsive guidance receptors, robo1 and robo2 (also designated roundabout 1 and 2). Interactions between the robo receptor and Slit ligand families of proteins initiate signaling cascades that repel axonal outgrowth. The arrangement of the extracellular domains of robo4 diverges significantly from that of all other robo family members. Robo4 is the only robo family member expressed in primary endothelial cells. It binds Slit and inhibits cellular migration in a heterologous expression system. Together, the robo proteins prescribe developmental paths during neural development. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of robo4 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 546-775 mapping within an internal region of robo4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 546-775 mapping within an internal region of robo4 of human origin |
| Entrez Gene | 54538 |
|---|
| Application Notes | recommended for detection of robo4 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
