Application
Western blot analysis of ULBP2 expression in HeLa whole cell lysate.| Product Name | ULBP2 Antibody (H-48) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 171-218 mapping near the C-terminus of ULBP2 of human origin |
| Modification Notes | Cytomegalovirus UL16 binding proteins, known as ULBPs, are GPI-linked glycoproteins that belong to the extended MHC class I family. ULBP proteins are ligands for the activating receptor, NKG2D/DAP10, which causes lymphocyte activation, resulting in the secretion of cytokines, such as interferon-gamma and tumor cell lysis. ULBPs stimulate cytokine and chemokine production from NK cells, CD8 alpha/beta T cells, and gamma/delta T cells. UL16, binds to three of the five known ligands for human NKG2D. UL16 is retained in the endoplasmic reticulum and cis-Golgi apparatus of cells and causes MICB to be similarly retained and stabilized within cells. Coexpression of UL16 markedly reduces cell surface levels of MICB, ULBP1, and ULBP2, and decreases susceptibility to natural killer cell-mediated cytotoxicity. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ULBP2, RAET1G and RAET1L of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 171-218 mapping near the C-terminus of ULBP2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 171-218 mapping near the C-terminus of ULBP2 of human origin |
| Entrez Gene | 80328 |
|---|
Application
Western blot analysis of ULBP2 expression in HeLa whole cell lysate.| Application Notes | recommended for detection of ULBP2, RAET1G and RAET1L of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
