| Product Name | Septin 12 Antibody (M-42) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-42 mapping at the C-terminus of Septin 12 of mouse origin |
| Modification Notes | Septins are members of a conserved family of cytoskeletal GTPases, specifically belonging to the large superclass of P loop GTPases. Septin proteins form homo- and hetero-oligomeric polymers that accumulate into higher-order filaments which may function as dynamic protein scaffolds. Septins play an important role in vesicle trafficking, apoptosis, cytoskeleton remodeling, infection, neurodegeneration, neoplasia and cytokinesis. Septin 12, also known as SEPT12, is a 358 amino acid cytoplasmic protein and filament-forming cytoskeletal GTPase that belongs to the Septin family. Widely expressed and existing as two alternatively spliced isoforms, Septin 12 expression levels are critical for mammalian spermiogenesis. Suggested to play a role in cytokinesis, Septin 12 can exist as a homodimer and interacts with both Septin 6 and Septin 11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Septin 12 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-42 mapping at the C-terminus of Septin 12 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-42 mapping at the C-terminus of Septin 12 of mouse origin |
| Entrez Gene | 71089 |
|---|
| Application Notes | recommended for detection of Septin 12 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
